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What is sickle cell disease?

What is sickle cell disease?

Sickle cell disease is a disorder that affects the red blood cells, which use a protein called hemoglobin to transport oxygen from the lungs to the rest of the body. The most common type of sickle cell disease is sickle cell anemia.

In most people, red blood cells are round and smooth. This round and smooth shape allows the cells to move easily through the blood vessels. People with sickle cell disease have abnormal hemoglobin, which is a protein found in the red blood cells.

sickle cell 1

The sickle cell hemoglobin can cause the red blood cells to change shapes, from the normal round shape into a crescent (or sickle) shape. The sickle shaped red blood cells are hard and sticky and do not pass well through blood vessels. As a result, blood vessels can sometimes become clogged, preventing blood from flowing through them. A clogged blood vessel is called an “occlusion.” Occlusions in blood vessels can lead to a painful sickle cell crisis.
Both children and adults who have sickle cell anemia have a hard time fighting infections. This is because sickle cell anemia can damage the spleen, an organ that helps fight infections. Infants and young children who have damaged spleens are more likely to get infections that can kill them within hours or days.

Pneumonia is the most common cause of death in young children who have sickle cell anemia. Meningitis, influenza and hepatitis are other infections that are common in people who have sickle cell anemia. Therefore, we must administer IV antibiotics and other drugs for hepatitis and/or meningitis when ordered.

Two forms of stroke can occur in people who have sickle cell anemia. One form occurs when a blood vessel in the brain is blocked. The other form occurs when a blood vessel in the brain bursts. A stroke can cause learning disabilities and/or lasting brain damage, long-term disability, paralysis or death. As with any stroke, nurses must carefully monitor all vital signs on a regular basis and a head-to-toe assessment must be completed daily.

While there is no cure for sickle cell disease, there are precautions for preventing painful sickle cell crises and treatments to provide relief during pain crises.

Please note that Someone who inherits only one sickle cell gene and a normal gene from the other parent will have the sickle cell trait, but not the disease



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About Temilola Waliu Globalwalyy

I am , the Found and Chief Editor of , Temilola waliu is a health Researcher. medical and fitness writer.I am a website Designer, logo and banner designer. Temilola Waliu is a Internet addict, a day without internet is just like a day without food..You can connect with me on Facebook +++ Twitter +++ Google Plus +++ Pinterest

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  1. Thank you very much for sharing this very informative article. I am a nurse by profession and it pains me to see kids who have this kind of disease. Yes, sickle cell disease has no cure and I hope one day, there will be a cure for this.

  2. Hi Dr. Temilola,

    I have heard a lot about sickle cell disease. It is one that still has no cure. Here, you have given me a better education of exactly how it works biologically.

    I thank you for bringing this topic up because it does not receive the attention it needs.


    • Twitter:
      Hey Donna, Yes you are right sickle cell disease has no cure, but it seems the world is getting silence on the disease, millions of people are dieing because of this same disease, are we just going to just keep shut about the deadly disease?

      Thanks to taking your time to visit my site..

  3. Twitter:
    Hi Dr. Temilola,

    This is my first time, or shall I say – my return visit to your blog :)

    Nice and informative post about sickle cell disease, and it’s the first time I’m reading about it too. I guess like they say prevention is better than cure, is there anything we can do to prevent this disease, other than living a healthy lifestyle and eating well.

    Thanks for sharing . Have a nice weekend :)

    BTW – The CommentLuv plugin isn’t working here, and shows some error.

    • Dr. Temilola Waliu Globalwalyy

      Dear Harleena, Am suprise to hear this is the first time you are actually hearing about sickle cell diseases, maybe its not a disease that can be easily contact , like Hiv,gonorrhea etc…

      Am Glad you are visiting my site, and the comment love is working just fine here…
      Thank you once again.

    • Am suprised to hear that you have never heard of the sickle cell disease, that just a mouth watering suprise…..

      If the site owner permit me, i will be coming here to write more about the diseases..

  4. This is lovely post.I am inspired from here.Can you more share with me.I will come back as soon.

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